References : Gilbert - Developmental Biology, Slack- developmental Biology.
Topics covered : Metamorphosis introduction and basics, primary and secondary larvae, direct and indirect development, tadpole characteristics, Adult characteristics, characteristics present in both tadpole and adult, metamorphic changes in anurans, characteristics that will not undergo any drastic change, Hormonal control of metamorphosis (T4 and T3), Types of changes in metamorphosis : Growth, death, remodeling, respecification, Growth (limbs, eye lids, neurons, binocular vision, Ipsilateral neurons, Death (RBC, Gills, Tail regression), Remodeling ( Intestine, LLS, Neurons, Head), Respecification (Liver enzyme of Urea cycle), comparison of excretion in organisms, Cases, Mechanism of Hormone action, secretory pathway, where T3 binds in nucleus?, Deiodinases, TR-alpha and TR-beta receptors, thyroid hormone signaling and mechanism, working of TR-RXR dimer, pre-metamorphosis, pro-metamorphosis, metamorphic climax, endocrinology of metamorphosis, cases, role of prolactin in metamorphosis, Regional specificty. etc.
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